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Differentiated thyroid carcinoma (DTC), arising from thyroid follicular epithelial cells, accounts for the vast majority of thyroid cancers. Despite being well-differentiated, papillary thyroid cancers may be overtly or minimally invasive. They may invade lymphatics but are less likely to invade blood vessels. Iodine-131 (131I) is routinely used to image patients after thyroidectomy to assess the presence of residual thyroid tissue with or without metastasis.
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