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Meta Description: The external genitalia are considered ambiguous whenever there is difficulty in assigning gender to a child based on the appearance of the external genitalia. It is a common presentation of children with disorders of sex development (DSD) and a cause of parental anxiety. Abnormalities of external genitalia occur in 1.7% of new born in developed countries.
In most developing countries, the prevalence is unknown; however reports of cases are on the increase.Globally, approximately 1 in 2000 children is born with DSD. The appearance of the external genitalia is a complex interaction between genetic and endocrine processes during fetal development. There are various causes of ambiguous genitalia; it can either resultfromover-virilisation or masculinization of 46, XX female from androgen excess, or under-virilisation or under-masculinization of 46 XY male due to a disorderin androgen synthesis or action.
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