Meta Description: Diarrheal illness remains one of the leading causes of morbidity and mortality worldwide, despite ongoing trials to understand its epidemiology, pathogenesis, and treatment. Shigellosis is one of the acute infectious disease that cause an estimated 150 million cases and 600,000 deaths annually, it is responsible for 10% of all cases of diarrhea among children <5 years of age living in developing countries and can cause disease after ingestion of 10 bacterial cells only So there is a need to revisit shigellosis epidemiology to see if it is following the global trend of diarrheal diseases, or if it has its own unique evolutionary profile.
Shigellosis caused by one of four serogroups with multiple serotypes: A (S dysenteriae, 12 serotypes); B (S flexneri, 6 serotypes); C (S boydii, 18 serotypes); and D (S sonnei, 1 serotype). They are transmitted by fecal-oral route, water, food, fomites, flies and direct contact to a diseased person or carrier. The symptoms include abdominal pain, tenesmus, watery diarrhea, and/or dysentery.
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