Meta Description: Treatment of complicated appendicitis in children with once daily CM has some important advantages including simple dosing schedule that can decrease the risk of mistake in drug administration, require the patient to be connected to the IV line for short time only once a day instead of most of the day for the triple antibiotics, may cause less IV line infection and may cost less.

AGM, or Ampicillin, Gentamicin, and Clindamycin (AGC) regimens are the standard triple antibiotic therapy for complicated appendicitis in children, providing broad-spectrum coverage for both aerobic and anaerobic gram-positive and gram-negative bacteria. The current approach to complicated appendicitis in children in our institution has been a nonoperative management including initial IV therapy with AGM, switching to oral amoxicillin/clavulanate after the patient became stable, afebrile and able to tolerate oral food and interval appendectomy 8 weeks after discharge.

For more details:

https://www.omicsonline.org/single-daily-dosing-of-ceftriaxone-and-metronidazole-is-as-safe-and-effective-as-ampicillin-gentamicin-and-metronidazole-2161-0665-3-177.php?aid=20601

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