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A common practice in gene expression studies is to use ‘housekeepers’, i.e., genes expected to be expressed at relatively constant levels across experimental conditions, to normalize data. The process is to divide an expression value by some composite of one or more stable housekeepers to remove the effect of processing and nuance variables. See more at www.omicsonline.org/open-access/ratios-and-housekeeper-normalization-2155-6180-1000252.php
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