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Nanocarriers have the potential to improve the therapeutic index of currently available drugs by increasing drug efficacy, lowering drug toxicity, and achieving steady state therapeutic levels of drugs over an extended period of time [3,4]. The association of rhodium (II) citrate with magnetic nanoparticles has the potential to increase the specificity of the cytotoxic action, since these complexes can be guided or transported to a target by the use of an external magnetic fiel.
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