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The discovery of antidepressant drugs in the 1950s led to the first biochemical hypothesis of depression, known as the monoamine hypothesis. This hypothesis proposes that an imbalance of certain brain chemicals is the key cause of depression. Research has investigated whether and to what degree the "reward and pleasure" chemical dopamine and, more recently, the "happiness" chemical serotonin, could be the neurotransmitters involved in the malady.
Proteinaceous infectious particles, also known as prions, are proteins in which the complex molecular three-dimensional folding process has simply gone astray. The ever-growing crowd of misfolded proteins forms the aggregates seen in the brains of patients with neurodegenerative disorders such as Parkinson's and Alzheimer's diseases...read more @ http://www.scitechnol.com/spine-neurosurgery.php
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