The threat of untreatable gonorrhea underscores the importance of identifying new treatment options, ensuring adherence to screening and treatment guidelines, including treatment of (infected) partners and increasing awareness among individuals on how they can best protect themselves from infection. Gonorrhea spreads through unprotected vaginal, anal and oral sex. Symptoms of the infection are often absent. Undiagnosed and untreated gonorrhea may lead to pelvic inflammatory disease, infertility, ectopic pregnancy (a pregnancy that occurs outside of the uterus) and/or chronic pelvic pain. Losing effective treatment will cripple our ability to fight and prevent gonorrhea, and will also leave patients at greater risk of serious health complications from untreated gonorrhea.