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In diagnostic medicine, the test that determines the true disease status without an error is referred to as the gold standard. Even when a gold standard exists, it is extremely difficult to verify each patient due to the issues of costeffectiveness and invasive nature of the procedures.See more at www.omicsonline.org/open-access/correction-of-verication-bias-using-loglinear-models-for-a-single-binaryscalediagnostic-tests-2155-6180-1000266.php