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Obesity has been associated with low testosterone in adult males and in pubertal boys. Therapy for hypogonadism with exogenous T may lead to testicular atrophy and later infertility. Hypogonadism, defined as a low serum T accompanied with a constellation of symptoms, such as fatigue, loss of libido, poor exercise tolerance along with reduced fertility (low sperm counts), is of growing concern to clinicians, as the prevalence of HG in the US has increased over time.
Citations: Bendre SV, Murray PJ, Basaria S (2015) Clomiphene Citrate Effectively Increases Testosterone in Obese, Young, Hypogonadal Men. Reprod Syst Sex Disord 4:155. doi:10.4172/2161-038X.1000155
Source: https://www.omicsonline.org/open-access/clomiphene-citrate-effectively-increases-testosterone-in-obese-young-hypogonadal-men-2161-038X-1000155.php?aid=63661
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