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Multiple sclerosis is not a fatal disease but it leads to progressing disability and complications which can be life-threatening. These include: chronic renal failure associated with urinary incontinence, bedsores (being a consequence of disability), aspiration pneumonia, suicides, and depression (both as a symptom of the disease itself and as a result of the progressing disability). MS patients commit suicide seven times more often than the general population. The progression of disability in most patients leads to permanent disablement and inability do live independently.