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Obesity and its comorbidities have become an important community health problem worldwide. Recent literature revealed that adipocytes not only store fat, but are also an endocrine organ which releases a variety of mediators. These mediators may manipulate, circulating lipid levels, blood pressure, and insulin resistance. Common co-morbidities related with obesity, such as hypertension, hyperlipidemia, and insulin resistance are associated with increased cardiovascular and renal disease, resulting in increased morbidity and mortality
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