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Polio is a viral disease also called infantile paralysis. It is a subgroup of picornavirdae family with three major serotypes as PV1, PV2 and PV3 respectively. Immunity against all these three types is essential for prevention against it to human being. This virus is usually transmitted through oral discharge from oral routes. Upon entrance into human body, the virus multiplies in the oral larynx and small intestine. It attacks the local lymphoid tissues and then enters into the main blood system of the body, while attacking the nervous system