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Protective Role of Grape Seeds Extract against Cadmium Toxicity in the Lung of Male Wistar Rats
Objective: This study was done on 40 male wistar rats to evaluate the curative and protective effect of grape seeds extract on oxidative damage, inflammatory and apoptotic insult on lung tissue induced by cadmium chloride toxicity.
Materials and Methods: The rats were classified to control group (group I), cadmium chloride group (group II), grape seeds extract group (group III) and mixture of grape seeds extract and cadmium chloride group (group IV). At the end of the experimental period, the lungs were collected and fixed in formalin saline (10%) for histopathological and immunohistochemical studies. Serum samples and frozen lungs were used for biochemical analyses....Read more
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