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While seedlings of large-seeded plants are considered to withstand resource restrictions and abiotic stresses more efficiently, plants with small seed sizes are considered more efficient colonizers due to their ability to produce greater numbers of seeds. On the other hand, seed size can be altered intraspecifically in response to environmental cues. Ecologists and evolutionary biologists had early observed this phenomenon. However, it is largely unknown the mechanism underlying why are seedlings of large-seeded plants considered to withstand drought stresses efficiently.