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In recent decades, the performance of digital cameras and computers has rapidly increased while their cost has decreased; thereby enabling machine vision and computer simulation to be applied in a range of sectors, for realising affordable andextensive potential benefits. This has resulted in considerable research efforts internationally; and over the last twenty years at the University of the West of England, Bristol, I have been researching into applications of machine vision and computer simulation in fields that have ranged from powder metallurgy (PM) to detection of skin cancer.