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The present study deals with improvement in aqueous solubility of aceclofenac using HPMC K-15M, PVP-K30 and Eudragit RS-100 in varying ratio by spray-drying at optimized condition. The samples of solid dispersion were subjected to fourier transform infra-red spectroscopy (FTIR), differential scanning calorimetry (DSC), powder X-ray diffraction morphology (PXRD), scanning electron microscopy (SEM), in vitro drug release and stability studies.Read more.
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