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B Cells Accumulate in the Cerebrospinal Fluid in Inflammatory Neurological Diseases

The contribution of B lymphocytes and their products to the pathogenesis of inflammatory diseases of the central nervous system is still not fully understood. Beside their role as precursors of antibody-secreting cells, B cells participate in the regulation of T cell activation through their antigen-presenting capacity, the production of cytokines and chemokines and the formation of ectopic germinal centers in intermeningeal spaces.... 

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