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α-L-Fucose in Histology: A Part of the Cancer Glycome Hiding in Plain Sight
Alpha-L-fucose (“fucose”) is a 6-carbon deoxy-sugar that is found to be contained in major blood group antigens, in Lewis minor blood group antigens and on many epithelial cells. Fucose is incorporated into numerous tumor-associated carbohydrate antigens, and appears to have important functional significance, as well as biomarker significance, in common human cancers..
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