|"Blood disorders malaria and African trypanosomiasis were enriched, suggesting preeclampsia may share downstream targets resulting in the systemic hypertensive state. Malaria is a nown risk factor for developing preeclampsia in tropical countries, further supporting the notion of preeclampsia as a blood disorder, and suggesting a possible causal molecular link between idiopathic and malarial induced preeclampsia. The results from the 12 studies indicate there is deregulation in the hemostasis pathway during preeclampsia. The markers are found in both tissue and serum ndicating it may be relevant in the etiology of preeclampsia and secreted into maternal circulation to induce systemic vascular function.
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Citation: Wong F, Cox B (2014) Proteomics Analysis of Preeclampsia, a systematic Review of Maternal and Fetal Compartments. J Proteomics BioinformS10: 001."