Leukemogenesis is induction and development of leukemia in bone marrow i.e a process in which successive transformational events enhance the ability of hematopoietic progenitor cells to proliferate, differentiate, and survive. From cells in the hematopoietic stem and progenitor cell compartment Leukemiaâs are monoclonal diseases that arise. Characterization of these clonal chromosomal aberrations, together with observed alterations in other growth-promoting genes, provides a useful framework for studying chemical leukemogenesis and for use in understanding the origins and development of leukemia in general. There are two models in Leukemogenesis: Acute myeloid leukemia, chronic myeloid leukemia.
Journal of blood disorders & transfusion facilitates the readers to go through a wide range of articles on leukemia and other blood disorders. These articles provide reliable source of information that can get to persistent redesigns and may help them to enhance the nature of consideration and the conclusion for patients
Last date updated on July, 2014