Blood Coagulation (thrombogenesis) is the intricate process by which blood forms clots. Disorders of coagulation can accelerate to an expanded risk of bleeding (hemorrhage) or obstructive clotting (thrombosis). Blood coagulation is quite moderated throughout biology; in all mammals, coagulation includes both a cellular (platelet) and a protein (coagulation factor) component. Exposure of the blood to proteins such as tissue factor starts changes to blood platelets and the plasma protein fibrinogen, a clotting component. Blood coagulation is an essential part of hemostasis, the discontinuance of blood loss from a damaged vessel, wherein a damaged blood vessel wall is secured by a platelet and fibrin-containing clot to quit bleeding and start repair of the damaged vessel. There are 13 known clotting factors which are called by their Roman numbers - factor I to factor XIII. A complex cascade of chemical reactions including these clotting factors rapidly happens beside a cut. Journal of Blood Disorders & transfusion publishs the work related all blood coagulation diseases of all major clinical and medical classifications. Journal of Blood Disorders & transfusion have a world class Editorial Board and maintains its quality publication with support of its editors in Peer review process.
Last date updated on July, 2014