|Hemorrhagic stroke which is a form of stroke that affects 20% of all stroke patients is a devastating condition for which new treatments must be developed. Current treatment methods are quite insufficient to reduce long term morbidity and high mortality rate, up to 50%, associated with bleeding into critical brain structures, into ventricular spaces and within the subarachnoid space. Brain hemorrhage stroke occurs in approximately 20% of all patients with a stroke There are two main categories of hemorrhagic stroke, intracranial hemorrhage including epidural hematoma, subdural hematoma and subarachnoid hemorrhage (SAH), and intracerebral hemorrhage (ICH) including intraparenchymal hemorrhage (IPH) and intraventricular hemorrhage (IVH). As a consequence of brain hemorrhage, enzymes involved in blood clotting and clot lysis are produced however, many of them have potential toxicities.
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