Gluten Ataxia

The significance of autoantibodies associated with neurological symptoms has been the focus of interest. Recent studies emphasized the pathogenic role of anti-gliadin antibody in gluten ataxia, an important disease of autoimmune cerebellar ataxia. To examine whether autoantibodies, including anti-gliadin antibody, play a pathogenic role, we analyzed the effects of CSF samples obtained from a Japanese patient with gluten ataxia on cerebellar synaptic transmission. The significance of autoantibodies associated with neurological diseases has been the focus of discussion. In most of autoimmune neurological disorders, it is not clear whether the antibody acts as a pathogenic agent causing symptoms, or it is produced as a result of cell-mediated autoimmune responses against neural structures. To confirm the pathogenic role of autoantibodies in the development of neurological symptoms. Autoimmune cerebellar ataxia is important since early diagnosis and therapy could relieve the symptoms, which is in contrast to spinocerebellar degeneration. The major two forms of the disease are gluten ataxia and GAD-Ab-associated ataxia. The open access journals are peer reviewed scholarly journals of in Histopathology. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.

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Last date updated on April, 2024