Stem cell therapy is a promising treatment option for these neurological diseases. There are many different treatment methods of PD. L-DOPA is still fundamental drug in early periods of PD, dopaminergic agonists, rasagiline use in initial treatment for the disease, Catechol-O-methyltransferase inhibitors are effective with motor fluctuations. Apomorphine is another drug that can be used non-oral. Deep brain stimulation is also a widely used treatment method. None of this treatment provides a cure for PD. Moreover, although their effects decrease, side effects are emerging but stem cell therapy would induce long-term clinical improvement. Stem cell therapy is one of the treatment methods in order to stop the progression of the disease and if possible return loss of function. It is not a realistic expectation that stem cells integrate to neural network by replacing lost motor neurons. The hope is the halting of motor neuronal death. There are currently ongoing trials of various types of stem cell transplantation.
Neurological diseases are caused by a loss of neurons and glial cells in the central nervous system (CNS) or peripheral nervous system. Effective treatment of these neurological diseases is currently impossible.
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Last date updated on September, 2020