Cachexia is defined as an extreme wasting condition with marked weight loss, anorexia, and lassitude. About half of all cancer patients show a syndrome of cachexia characterized by loss of adipose tissue and skeletal muscle mass. Such patients have a decreased survival time compared with that of patients without weight loss. Abnormal metabolism is thought to be the basis of the cachexia status in advanced cancer patients. Cachexia induces the cytokines, in particular tumor necrosis factor (TNF)-Î±, IL-1, and IL-6, is thought to inhibit the activity of lipoprotein lipase (LPL), and thereby induces weight loss as a result of reduced fat accumulation in the tissues. Therefore, it is thought that emaciation of cancer patients might be prevented and cachexia improved by increasing LPL activity
The open access journals are peer reviewed scholarly journals of Obesity & Weight Loss Therapy. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.
Last date updated on September, 2014