|Epigenetics refers to the heritable changes with respect to the gene expression that occurs without any change in the DNA sequence of an organism. DNA Methylation and Histone modifications are the two main epigenetic mechanisms. Epigenetic does not involve the change in the genome but it refers to the change in the expression patterns in the genome. Thus it has chances to result in cancerous growth. The open access journals are peer reviewed scholarly journals of adenocarcinoma. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.