|Mutagenesis is the process by which the a particular base pair in a genome is completely changes, in simple that the particular genome changed, mutated. This mutation can be a spontaneous reaction or a induced reaction. Certain mutation is helpful for the organism to adjust itself to its habitat while certain result in cancerous growth. This is because; the mutation in genome can result in the formation of a truncated protein. These proteins either switch off or on the essential pathways resulting in cancerous growth. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.