Pharmacology Top Open Access Journals|OMICS International|Clinical Case Reports

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Pharmacology Top Open Access Journals

Pharmacology is the branch of medicine and biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous molecule which exerts a biochemical and/or physiological effect on the cell, tissue, organ, or organism There are more than 70 types of autoimmune diseases. Till now the cause of autoimmune disease is not well know. Autoimmune diseases can be categorized in to two types a) systemic autoimmune diseases b) localized autoimmune diseases. Systemic autoimmune diseases affect multiple organs. Localized autoimmune diseases target one organ. Systemic lupus erythematosus comes under systemic autoimmune diseases. Researchers found antibodies targeting the host’s DNA in Systemic lupus erythematosus where many of these antibodies are toxic and have the ability to penetrate in to the living cells and nuclei. The lupus antibody, known as 3E10, is not only benign but has the capacity to penetrate both healthy and malignant cells and cell nuclei, Researchers though that 3E10 can be used as a vehicle for drug delivery. They further found that 3E10, when used alone, could kill cancer cells with DNA repair deficiencies such as those with mutations in the BRCA2 gene.
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Last date updated on May, 2021