A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.
Cell signaling is part of the convoluted scheme of communication which rules the rudimentary cellular activities and coordinates the cell activities. The ability of cells to perceive and rightly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as usual tissue homeostasis. Mistakes in cellular data processing are responsible for diseases such as autoimmunity, cancer, and diabetes with comprehending of cell signaling, diseases can be treated competently and, theoretically, artificial tissues can be created. Cell signaling has been most extensively studied in the context of human infections and signaling between cells of a single organism. However, cell signaling may furthermore occur between the cells of two distinct organisms. Cells communicate with each other via direct contact (juxtacrinesignaling), over short distances (paracrine signaling), or over large distances and/or scales (endocrine signaling). Many cell signals are conveyed by molecules that are issued by one cell and move to make communicate with another cell. A large number of diseases are initiated by defects in signalling pathways. The nature of these defects and how they are induced varies tremendously. Pathogenic organisms and viruses, numerous of which can hinder with signalling events, origin some of these defects. There are other infections that can be traced to defects in the function of cell indicating pathways. The notion of signalsome remodelling and infection presents a structure for contemplating how defects in signalling pathways can outcome in disease. It is convenient to distinct these defects into phenotypic remodelling of the signalsome and genotypic remodelling of the signalsome.
Last date updated on July, 2014