Cell-to-cell communication is the fundamental mechanism that enables multicellular organisms to maintain tissue homeostasis and normal cellular functions. Recent studies have demonstrated that extracellular vesicles, including exosomes and microvesicles, may act as a crucial mediator of intercellular communication. It is well-established that EVs are small membrane vesicles secreted from numerous cell types, including immune cells, tumor cells, and stem cells. In addition, EVs have been found in various body fluids, such as blood, saliva, and urine. EVs are secreted either in a constitutive or regulated manner. For instance, a number of tumor cells release EVs constitutively, whereas primary B cells secrete EVs when stimulated with potent activation signals, such as cytokine.
Extracellular Vesicles as an Emerging Paradigm of Cell-to-Cell Communication in Stem Cell Biology- Chul-Woo Kim.
OMICS Group International is one of the leading Open Access Publishers which is running 700+ peer-reviewed journals. Cell & Developmental Biology is one of the best open access journals with the wide range of area that deals with cell biology and developmental aspects of cell.
Last date updated on June, 2014