"Chitin is one of the most abundant renewable biopolymers on the biosphere. It is the primary structural component of fungal cell walls and arthropod exoskeletons. Chitin is the homopolymer of Ã-1, 4 linked N-acetyl glucosamine. Chitinases are the enzymes which involve in the degradation and effective recycling of insoluble chitin in nature by hydrolyzing the Ã-1, 4 glycosidic linkages. Based on amino acid sequences of the catalytic domains, chitinases are classified into two phylogenetically distinct families (GH18 and GH19), which are volutionarily unrelated and have variations in protein sequence and ructure. Chitinases are ubiquitous and found in a broad range of taxons with diversified functions. There are many reports on the controlled expression of microbial chitinases with chitin or its oligomers as inducers and glucose as repressor.
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Last date updated on July, 2014