High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Cirrhosis is a disease related to the liver which is characterized by loss of liver cells which is replaced by fibrosis. The major causes of cirrhosis are alcohol and viral hepatitis B and C. It can be diagnosed by liver biopsy. The slowly progressing disease in which healthy liver tissue is replaced with scar tissue, eventually preventing the liver from functioning properly is termed as liver cirrhosis. The scar tissue blocks the flow of blood through the liver and slows the processing of nutrients, hormones, drugs, and naturally produced toxins. It also slows the production of proteins and other substances made by the liver. The relationship between liver and blood plays a vital role in maintain bodys various functions. However, in cirrhosis this relation between blood and liver gets affected further leading to many other complications.
Last date updated on September, 2014