Rheumatoid arthritis (RA) is an autoimmune disease, associated with a chronic inflammatory status, and increased levels of cytokines which are implicated in the destruction of joints. The disease can develop at any age but most often occurs in people between age 25 and 50, and is more common among women, with a worldwide prevalence rate of approximately 1%. Periodontal disease (PD) is an infection of the tissue that surrounds and supports the tooth structure, resulting also in a chronic inflammatory status. The severe generalized form of periodontal disease has a global prevalence rate of 5%-15%. Several associations have been reported between PD and other diseases such as RA, hypertension, and diabetes.
Mohammed Hammoudeh: Ahmed Al-Momani: Magdi Hassan Abdelrahman: Prem Chandra and Samer Hammoudeh, Prevalence and Association of Periodontal Disease among Rheumatoid Arthritis Patients in Qatar: A Cross Sectional Study
âRheumatoid Arthritis (RA) is a chronic systemic auto immune inflammatory disease affecting mostly the joints as well as other organs. Genetic factors may play a big role in the pathogenesis of RA. Genes encoded within HLA DRB1 provide the most consistent genetic evidence. It is well recognised that HLA DRB1 shared epitope alleles largely influence development of seropositive RA and specifically Anti CCP positive disease. Smoking is a very important environmental factor. Other suggested environmental factors include obesity, silica dust, exposure to mineral oils and socio-economic class. Viruses and mycoplasma organisms may also be implicated.
O O Adelowo and MKN Bello, Systemic Autoimmune Diseases: Not So Rare in Black Africans
Last date updated on July, 2014