Stem cells are considered as a boon for mankind in the medical world. But the limited supply of stem cells has paused the progress on many fronts. Researchers working on embryonic like stem cells from adult donors. This process has involvement of huge number of genes which are like double edged swords as they also trigger cancer. A single gene which can produce billions of supercharged stem cells, by which body repair itself has been patented. Induced pluripotent stem (iPS) cell technology evolved by the rigours efforts of university of central florida(UCF) which minimizes the risk. This technology turns into magic wand and changes the landscape of regenerative medicine.
NANOG gene codes for nanog protein involved in the selfrenewal of embryonic stem cells. This is considered as a key factor for pluripotency of embryonic stem cells and gives potential to derive any type of cells (endoderm, ectoderm, mesoderm). Presence of more amounts of Nanog protein in the mouse embryonic stem cells caused selfrenewal but in the absence caused differentiation of embryonic stem cells into functionally different cells. This gives very important clue to the medical world.
The literal understanding of this gene will lead into new avenue where patient own cells can be used for curing many degenerative diseases and sprouts the healing power hidden within the body.
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Last date updated on September, 2014