Retina is a part of the central nervous system (CNS) responsible for visual perception and processing. The retina is a complex organ and, like the CNS, it is also an immune privilege site, which has a blood retinal barrier (BRB) - the inner BRB formed by tight junctions of the endothelium and the outer BRB form by the retinal pigment epithelium (RPE). Retinal capillaries are covered by pericytes at a ratio of 1:1 with endothelial cell, which is the highest pericyte coverage in the entire vascular system. Retinal neurons are arranged in three distinctive layers - the photoreceptor layer or outer nuclear layer (ONL), which anchors at RPE, the bipolar layer or inner nucler layer (INL), and the ganglion cell layer (GCL).
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Last date updated on April, 2021