|Drug side effect is an effect that is secondary or unintended consequence of the drug administration in the body together with its intended purpose. The side effects of the drug can be either therapeutic or harmful to the body or a part of it. The drug side effects may vary from individual to individual and is dependent upon factors like age, gender, weight, disease, etc. The drug side effects can occur when starting or ending a drug medication regimen or while increasing or decreasing the dosage of it. In order to minimize the side effects of a drug, the current dosage may be adjusted or another medication can be prescribed. Also the lifestyle and or dietary changes may help to minimize the side effects of a drug. From a simple to the most sophisticated prescribed drug, all drugs come with side effects. The most common side effects for drug taken internally involve nausea or upset stomach, though it only happens to a handful of users. As compared to drugs applied externally skin irritation or allergy is commonly noticed. The open access journals are peer reviewed scholarly journals of Clinical & Experimental Pharmacology. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.