Experimental pharmacology is the division of pharmacology with an added focus on the experimental study of chemicals that requires an intimate knowledge of the biological systems being affected or under treatment. With the knowledge in the streams of cell biology and biochemistry been increasing the field of experimental pharmacology has also changed substantially. Now it has become possible through molecular analysis of the receptors on the cell surface to design chemicals that act on specific cellular signaling or metabolic pathways by affecting the sites directly on the cell-surface receptors which modulates and mediates the cellular signaling pathways and thereby controls cellular functioning. A chemical from the pharmacological point-of-view has various properties like half-life of active pharmaceutical ingredient, volume of chemical distribution, desired or toxic effects on the body, etc. A medication is said to have a therapeutic index or therapeutic window which describes the ratio of desired effect to toxic effect. Development of medication is thereby a vital concern to medicine. The metabolic stability and the reactivity of a candidate drug compound have to be assessed for drug metabolism and toxicological studies. Journal Article is sometimes called a Scientific Article, a Peer-Reviewed Article, or a Scholarly Research Article. Together, journal articles in a particular field are often referred to as The Literature. Journal articles are most often Primary Research Articles. However, they can also be Review Articles. These types of articles have different aims and requirements. Sometimes, an article describes a new tool or method. Because articles in scientific journals are specific, meticulously cited and peer-reviewed, journal databases are the best place to look for information on previous research on your species. Without a background in the field, journal articles may be hard to understand - however, you do not need to understand an entire article to be able to get valuable information from it.
Last date updated on June, 2014