Experimental pharmacology is the division of pharmacology with an added focus on the experimental study of chemicals that requires an intimate knowledge of the biological systems being affected or under treatment. With the knowledge in the streams of cell biology and biochemistry been increasing the field of experimental pharmacology has also changed substantially. Now it has become possible through molecular analysis of the receptors on the cell surface to design chemicals that act on specific cellular signaling or metabolic pathways by affecting the sites directly on the cell-surface receptors which modulates and mediates the cellular signaling pathways and thereby controls cellular functioning. A chemical from the pharmacological point-of-view has various properties like half-life of active pharmaceutical ingredient, volume of chemical distribution, desired or toxic effects on the body, etc. A medication is said to have a therapeutic index or therapeutic window which describes the ratio of desired effect to toxic effect. Development of medication is thereby a vital concern to medicine. The metabolic stability and the reactivity of a candidate drug compound have to be assessed for drug metabolism and toxicological studies. Scientific journal is a periodical publication intended to further progress of science, usually by reporting novel research. There are thousands of scientific journals in publication, and many more have been published at various points in the past. Most journals are highly specialized, although some of the oldest journals publish articles and scientific papers across a wide range of scientific fields. Scientific journals contain articles that are peer reviewed, to ensure that articles meet the journal's standards of quality, and scientific validity.The publication of the results of research is an essential part of the scientific method. If they are describing experiments or calculations, they must supply enough details that an independent researcher could repeat the experiment or calculation to verify the results. Each such journal article becomes part of the permanent scientific record.
Last date updated on June, 2014