Toxicokinetics is the study of toxicant time course in terms of metabolism, absorption and excretion. Toxicokinetic study is the method of characterization of the toxin activity. The study deals with the overall processes the toxin undergoes after entry into the body or else how body handles the toxin. Study involves the analysis from initial satge of absortion to final stage of excretion and also the ability of toxins to pass the various biological memberanes are also analysed. The dose responses and concentration variations in the course of time is also dealt in toxicokinetic studies. Both invitro and in silico approaches are made for the analysis of different parameters. Toxicokinetic analysis information provides the information for chemical hazard identification and management.
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Last date updated on September, 2024
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