|Xenobiotics as the name signifies âstrangersâ are compounds that are foreign to human body. Xenobiotic compounds include natural as well as synthetic compounds such as pesticides, drugs, additives, heavy metals, food additives etc. The accumulation of these compounds in the body will cause depletion of cells and adverse effect on metabolism. In lower doses some of the Xenobiotic compounds have beneficial functions such as pharmaceutical and drug activities. Food and medication is the common pathway of Xenobiotic entry into body. Xenobiotic compounds enter the cells through diffusion, active transport and endocytosis. The metabolism of the Xenobiotics occurs mainly in liver.
The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.