Chronic Arterial Occlusion

chronic arterial occlusion is surgery or endovascular treatment. However, there is no choice but drug treatment for patients for whom these invasive treatments are not indicated. Currently, there is no drug with proven efficacy for the treatment of CLI. Cilostazol and naftidrofuryl (not marketed in Japan) have been demonstrated to be effective in the treatment of IC in several large-scale clinical studies. Cilostazol is recommended as the first-line drug for the treatment of IC. Cilostazol has been reported to improve claudication distance by approximately 50%, but there is no evidence to support the effectiveness of cilostazol in preventing the progression from IC to CLI. Given these circumstances, there is an urgent need to develop more effective techniques for the treatment of chronic arterial occlusion

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Last date updated on September, 2024