Multipotent mesenchymal stem cells (MSCs) derived from bone marrow have demonstrated great promise in regenerative medicine. A wealth of literature has documented the potency of MSCs to differentiate into many types of cells beyond their germinal boundary. Moreover, MSCs can also secrete paracrine soluble factors to modulate local cells to promote damage recovery. In order to achieve these effects, MSCs are required to be physically present in target tissues or organs. MSCs have shown some tropism for sites of damage tissues.
Last date updated on July, 2014