Cognition is the mental act or process by which knowledge is acquired, including perception, intuition, and reasoning. Cognitive impairment is the strongest determinant of poor functional outcomes. Cognitive deficits are evident at the time of the first psychotic episode; they persist and may worsen in midlife and late life. Conventional psychopharmacology has only minimally improved cognition. Mounting evidence of structural abnormalities as well as neuroplastic, neurochemical and circuitry impairments suggest potential etiologies for understanding the altered neurological functions underlying cognitive deficits in schizophrenia. These deficits are also manifest in intentionality, or Theory of Mind (ToM) .
It is increasingly becoming apparent that patients with Juvenile Myoclonic Epilepsy (JME) experience difficulties with various aspects of cognition. Studies that have attempted to find specific seizure-related factors contributing to and predicting cognitive dysfunction have provided conflicting and inconclusive results .
Last date updated on June, 2014