A cold-induced inflammatory mechanism gradually reduced fat thickness in 90 days after a 30- to 60 minute cold plate exposure to the skin surface. In vitro examination of the adipocytesâ response to cold showed that the cooling of adipocytes to temperatures above freezing but below normal body temperature resulted in apoptosis â mediated cell death, which suggested that cryolipolysis produced an apoptotic injury in the adipose tissue. Furthermore, the subsequent inflammatory response may cause additional damage to those adipocytes not immediately affected by the cold exposure
High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on September, 2014