Docking is a method which predicts the preferred orientation of one molecule to a record when bound to each other to form stable complex knowledge of the preferred orientations in turn may be used to predict the binding strength of association or binding affinity between two molecules. Docking is frequently used to predict the binding orientations of small molecules drug candidates to protein targets in order to in turn predict the affinity and activity of the small molecule. The receiving molecule that primarily binds to a small molecule or another protein or a nucleic acid called receptor. A molecule that forms the complementary partner in the docking process called ligand. Vs K.Ramanathan, Structure Based Drug Designing for Diabetes Mellitus.
Last date updated on December, 2020