Generally, many drug side effects are caused by the interactions between drugs and undesired proteins which are different from the target receptors of the drugs. Considering such backgrounds, scientists tried to find the undesired proteins interacting with the drugs, which can induce some side-effects. This method is to explore the proteins which can bind drugs to various kinds of proteins whose 3D structures have been already revealed. vs Nagata M, Development of reverse fitting system and the application to predict side effects. The online journal is an essential reading to all pharmaceutical scientists involved in research in drug design and discovery.
Last date updated on April, 2021