Drugs are substances that exert some kind of physiological or biochemical effect on our bodies. They may be single compounds or mixtures, and their effects may be beneficial or harmful. All drugs interact with specific targets, which are usually proteins but in some cases DNA or RNA. Drugs work either by stimulating or blocking the activity of their targets. Today, more systematic approaches are used. High-throughput screening is used to test thousands of potential targets with thousands of diverse chemical compounds in order to identify promising lead compounds (chemical entities that interact with targets and therefore have potential as drugs). The alternative method of rational drug design involves the design and synthesis of compounds based on the known structure of either a specific target or one of its natural ligands. The results of the Human Genome Project and human pathogen genome projects provide many new potential drug targets. For this reason, target identification must be followed by target validation, which confirms the likelihood that interfering with the target protein will impact on the disease.
OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals. Each and every article undergoes a peer-review process to assess the quality of the article. Generally, these publications appreciate articles those that are accessible even to those people who are not specialist in the field but are interested in those research topic. These journals are periodical publications that are intended to share the progress of science. OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals.
Last date updated on September, 2014