Drug disposition is the knowledge about the fate of a drug such as its absorption, distribution, metabolism, and excretion, known by the acronym ADME and its pharmacokinetics. The pharmacokinetics describes the rates of these processes and of concentration-time relationships. In preclinical and early clinical drug development, information about the factors influencing drug disposition used to predict drug interaction potential, estimate and understand population pharmacokinetic variability, and select doses for clinical trials.
Scholarly peer review is the process of subjecting an author's scholarly work, research, or ideas to the scrutiny of others who are experts in the same field, before a paper describing this work is published in a journal. The work may be accepted, considered acceptable with revisions, or rejected. Peer review requires a community of experts in a given (narrowly defined) field, who are qualified and able to perform reasonably impartial review.
Last date updated on September, 2014