Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell. The Epigenetic modifications are reversible modifications on a cellâs DNA or histones that affect gene expression without altering the DNA sequence. Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis. The study of epigenetics on a global level has been made possible only recently through the adaptation of genomic high-throughput assays and The mechanisms governing phenotypic plasticity, or the capacity of a cell to change its state in response to stimuli, have long been the subject of research. The Classical views have attributed phenotypic variation to differences in primary DNA structure, be it through aberrant mutation or an inherited sequence allele.
Open Access journals are the major source of knowledge for young and aspiring generations who are keen in pursuing their careers in science. This system provides easy access to networks of scientific journals. Authors who contribute their scholarly works to Open Access journals gain remarkable reputation as the research scholars explore these works extensively. This process assures considerable impact factor for the journal and good reputation to the authors that add value to their Academic Performance Index (API) Score. Open access journal articles are essentially peer-reviewed and available for access through the directory of Open Access journals. OMICS Group International supports this system and provides access to 700+ peer-reviewed journals with no restrictions and thus promotes the Open Access movement with a view to promote scientific advancements.
Last date updated on June, 2014